Dosing

Clinical description

• The dose of NVP syrup or 2P tabs remains the same for the whole 6-week period – do not change

the dose according to age or body weight.

• Use the standard dose (1.5ml NVP syrup or 1⁄4 tablet of 2P) if birth weight is unknown (home birth,

no scale).

• Give 1⁄4 tablet of 2P to high-risk infants weighing 3kg or above twice daily for 6 weeks
• Give NVP syrup to high-risk Infants weighing less than 3kgs once daily for 6 weeks

Table 22: Dosing of NVP syrup (10mg/ml) and 2P tabs (AZT/3TC/NVP) for infant prophylaxis Birth weight Low risk High risk 2500g or less 1.0 ml NVP 24-hourly 1.0 ml NVP 24-hourly 2500 -3000g 1.5 ml NVP 24-hourly 1.5 ml NVP 24-hourly 3000g or above 1.5 ml NVP 24-hourly 1⁄4 tab 2P 12-hourly unknown 1.5 ml NVP 24-hourly 1⁄4 tab 2P 12-hourly 110 Newborn care and postnatal follow up