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21.3.3

Timing and duration

Clinical HIV Guidelines, 5th Edition, 2022. Chapter 21, Newborn care and postnatal follow up.

Clinical description

  • Start giving infant prophylaxis as soon as possible after birth – the earlier, the more effective.
  • Infant prophylaxis can be started anytime between birth and 4 weeks of age if the mother presents

late. Starting prophylaxis later is less effective and may cause drug-resistant HIV if the baby is already infected (and needs to start ART).

  • Stop giving prophylaxis when the infant is 6 weeks old. The infant will receive less than 6 weeks of

prophylaxis if it has been started late.

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