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5.3.1

Indications for Platelets Use

Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 5, Blood and Haematology.

Clinical Description

  • Bleeding due to thrombocytopenia because of defective platelet production such as aplastic anaemia or leukemia.
  • Increased consumption e.g., DIC
  • Dilutional effects e.g., in massive transfusion

All patients needing platelets need further investigations, please refer to Central Hospital.

Dose:

  • 1 unit per 10kg
  • For infants under 10 kg, 5ml/kg
  • Cross-matching is not required
  • Caution: platelet transfusion not usually indicated in ITP and TTP unless if patient is bleeding or undergoing invasive surgery

Side effects:

  • Febrile, non-haemolytic and allergic reactions are common in patients receiving multiple transfusions.
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