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7.5.3

Acute Gastroenteritis in Children

Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 7, Gastrointestinal Conditions.

Clinical Description

  • Passage of more than 3 loose stools in a day.

Causes

  • Infection: majority are caused by viruses, bacteria, parasites, Toxins, Drugs

Malabsorption: e.g. lactose intolerance and Food Protein Induced Entero-Colitis

Syndrome (FPIES).

Signs and Symptoms

  • Shock
  • Vomiting
  • Diarrhoea
  • Failure to thrive
  • Abdominal pain

Investigations

  • Stool microscopy and culture
  • Random blood glucose
  • Blood gas
  • Urea, electrolytes, and Creatinine
  • FBC

Treatment

  • Assess nutritional status. If malnourished, refer to malnutrition protocol
  • Assess dehydration and treat accordingly

Classification Signs and Symptoms Treatment

Severe Dehydration Two or more of the following signs:

Lethargy/unconsciousness

Sunken Eyes

Unable to drink/drinks poorly

Skin pinch goes back very slowly (≥2seconds)

PLAN C

Some Dehydration Two or more of the following signs:

Restlessness/irritability

Sunken eyes

Drinks eagerly/thirsty

Skin pinch goes back slowly

PLAN B

No Dehydration Not enough signs to classify as some or severe dehydration

PLAN A

  • Plan C: see severe dehydration protocol
  • Plan B: give 75ml/kg ORS over 4 hours
  • Plan A give ORS 5ml/kg after each loose stool.
  • Continue breastfeeding or give extra fluid.
  • Correct electrolyte imbalances.
  • Zinc 10mg PO 24 hourly < 6 months and 20mg if > 6months old for 10 days.
  • ONLY give antibiotics if bloody diarrhoea or if child is toxic.
  • Ciprofloxacin 10mg/kg PO 12 hourly for 5-7 days or Ceftriaxone 25 mg -50mg/kg IV 24 hourly for 5 days if not tolerating orally.

DO NOT give antiemetic’s or anti-motility drugs in children.

Complications

  • Acute Kidney injury
  • Electrolyte imbalance
  • Haemolytic Uraemic Syndrome (HUS)

Complications and Referral Criteria

Persistent diarrhea not responding to treatment

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