11.2
Cancer of the Cervix
Guidelines for Management of Sexually Transmitted Infections, 5th Edition, 2025. Chapter 11, STI with Specific Causes.
Clinical description
- Almost all cervical cancer is caused by persistent HPV infection. Early stages are asymptomatic; advanced CxCa can present as AVD and LAP.
- Speculum exam is essential to avoid missing cervical cancer.
- Screening methods: VIA (visual inspection with acetic acid), Pap smear, HPV DNA testing (Xpert).
- HPV vaccination is very effective — scheduled for girls aged 9–14 before first sex.
- Consider genital schistosomiasis as a differential diagnosis for cervical cancer.
Follow Malawi Cervical Cancer Guidelines for prevention, screening and treatment.
Need this without data?
The app holds every guideline on your device, with calculators, bookmarks and notes.