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8.5

Provision of CPT

National TB Management Guidelines, 2018 Edition. Chapter 8, TB and HIV.

Clinical description

All HIV-positive TB patients should be started on CPT to reduce the risk of death and the occurrence of opportunistic infections. If possible, CPT should be started on the same day that the patient’s HIV-positive status is determined. Once CPT is started, it should be given for life.

The following are contraindications to cotrimoxazole:

  • Known severe drug reaction to sulpha-containing drugs,
  • Severe megaloblastic anaemia or pancytopenia,
  • End-stage renal disease.
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